Bcl-2; C-Terminal Truncated; 1PC X 50UG

Code: PF126-50UG D2-231

Application

Neutralization (see biological activity)

Biochem/physiol Actions

EC50 = 100-300 nM based on its ability to inhi...


read more

Your Price
€653.30 EACH
€803.56 inc. VAT

Application

Neutralization (see biological activity)

Biochem/physiol Actions

EC50 = 100-300 nM based on its ability to inhibit 54 nM caspase-8-cleaved human Bid-mediated release of cytochrome c from isolated mouse liver mitochondria

General description

Recombinant, human Bcl-2 without the 17 amino acid mitochondrial targeting sequence at the C-terminus, fused to a His Tag™ sequence, and expressed in E. coli. The truncated protein retains the ability to neutralize pro-apoptotic Bcl-2 family members.

Recombinant, human Bcl-2 without the 17 amino acid mitochondrial targeting sequence at the C-terminus, fused to a His-Tag™ sequence and expressed in E. coli. The truncated protein retains the ability to neutralize pro-apoptotic Bcl-2 family members.

Legal Information

HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Packaging

50 µg in Glass bottle

Please refer to vial label for lot-specific concentration.

Physical form

In 100 mM KCl, 10 mM HEPES, 20% glycerol, pH 8.0.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Warning

Toxicity: Standard Handling (A)

assay≥95% (SDS-PAGE)
biological sourcehuman
formliquid
manufacturer/tradenameCalbiochem®
Quality Level100
recombinantexpressed in E. coli
shipped inwet ice
storage conditionavoid repeated freeze/thaw cycles, OK to freeze
storage temp.−20°C
This product has met the following criteria to qualify for the following awards:



PROCEED TO CHECKOUT

HAVE AN ACCOUNT? LOGIN


GUEST CHECKOUT

Proceed as a guest. You will have the option to register to access exclusive pricing and stock availability features after checkout.